Hundreds of Palestinian protesters are clashing with Israeli security forces in the West Bank cities of Hebron, Bethlehem and Ramallah.
The clashes began after Friday midday prayers in a show of rage over US President Donald Trump's decision to recognise Jerusalem as Israel's capital.
Protesters threw stones at Israeli troops who responded with tear gas and rubber bullets.
In Gaza, thousands took to the streets and marched on Friday to denounce Trump's proclamation.
In Bethlehem, masked youth burned tyres and threw stones at Israeli troops. Some tear gas was used in response.
There were also protests in Ramallah. Several people have been detained.
Thousands of Palestinian worshippers also are rallying outside Jerusalem's Al Aqsa Mosque, a flashpoint site in the holy city.
Israel has always regarded Jerusalem as its capital, while the Palestinians claim East Jerusalem - occupied by Israel in the 1967 war - as the capital of a future Palestinian state.